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한국인 남녀의 혈중지질과 식이 섭취와의 상관관계 연구

Title
한국인 남녀의 혈중지질과 식이 섭취와의 상관관계 연구
Other Titles
Correlation coefficient between Dietary intakes and Serum lipid levels of Korean Adult Males and Females
Authors
정미숙
Issue Date
2008
Department/Major
임상보건과학대학원 임상보건학과임상영양학전공
Publisher
이화여자대학교 임상보건과학대학원
Degree
Master
Abstract
본 연구는 2008년 3월 17일부터 4월 16일까지 경기도 소재 대학병원 건강진단센터에서 건강검진을 받은 검진자 293명의 신체계측, 혈액성분 및 혈압, 생활습관, 식습관, 영양소 섭취량을 조사하여 성인 남녀의 혈중지질 농도에 영향을 주는 요인을 분석하고자 수행하였다. 고지혈증 치료지침의 혈중지질 농도 기준에 따라 혈중 총콜레스테롤이 240ml/dl 이상 혹은 중성지방이 200ml/dl 이상인 경우를 위험군(Risk group), 혈중 총콜레스테롤이 200ml/dl 미만이며 중성지방이 150ml/dl 미만이 경우를 정상군(Normal group), 위험군과 정상군 사이를 경계군(Borderline group)으로 분류하였다. 각 군별 1일 평균열량 섭취는 정상군 1,818.3±22.5kcal, 경계군 1,803±36.3kcal, 위험군 1,999.5±45.9kcal 으로 정상군에 비해 위험군이 유의적으로 높았으며, 다량 영양소의 당질・지질・단백질 섭취량에서 정상군에 비하여 위험군이 유의적으로 높았다. 아연 영양소를 제외한 미량 영양소 및 섬유소 섭취량에서는 정상군, 경계군, 위험군간의 유의적인 차이가 없었다. 각 군별 대상자의 체질량지수・체중・허리둘레・체지방율 평균은 정상군에 비해 경계군, 위험군이 유의적으로ⅴ 높았으며, 혈압에서도 수축기 혈압, 이완기 혈압 모두 정상군에 비해 위험군이 유의적으로 높았다. 흡연・운동・음주여부의 생활습관에 따른 정상군, 경계군, 위험군간의 유의적 차이가 없었으며, 식습관 상태에서도 정상군, 경계군, 위험군간의 유의적인 차이가 없었다. 혈중지질 농도에 영향을 미치는 요인 분석 결과, 생활습관 중 흡연여부에서 ‘현재도 피우고 있다’ 고 응답한 경우 혈중 중성지방 농도가 유의적으로 높았으며, 음주횟수에서 ‘매일 마신다’ 라고 응답한 경우 혈중 콜레스테롤, 혈중 중성지방 농도 모두 유의적으로 높았다. 한편 연구 대상자들의 혈중 중성지방, 총콜레스테롤 농도에 따라 경계・위험중성지방군, 경계・위험콜레스테롤군으로 분류하여 영양소 섭취량을 비교한 결과 위험중성지방군인 대상자에서 열량・당질・지질・단백질 섭취량이 유의적으로 높았으나, 위험콜레스테롤군 대상자에서는 유의적인 차이가 나타나지 않았다. 영양소 섭취와 혈중지질간의 상관관계 분석 결과, 열량・당질・지질・단백질 섭취량이 혈중 중성지방 농도와 양의 상관관계를 나타내었고, 당질 섭취량과 HDL-콜레스테롤 농도는 음의 상관관계를 나타내었다. 그 밖에 체질량지수와 혈중 중성지방, 총콜레스테롤 모두 양의 상관관계를 나타내었다. 본 연구 결과를 종합해 볼 때 영양소 섭취량, 체질량지수, 혈압, 흡연, 음주 등이 혈중지질 농도에 영향을 미치는 요인으로 나타났다. 식이섭취에서는 열량・당질・지질・단백질 섭취량이 많을수록 혈중 중성지방 농도를 높이고, 당질 섭취량이 많을수록 HDL-콜레스테롤을 낮추는 것을 알 수 있었다. 따라서 우리나라 국민의 식이섭취 패턴과 관련하여 각각의 영양소와 blood lipid profile 에 영향을 미치는 식이섭취 요인 연구가 더 이루어져야 할 것으로 사료된다.;This study's purpose was to analyze factors that affect blood lipid levels of adult males and females, which was done by analyzing anthropometric measurements, constituent parts of the blood, dietary patterns and dietary intakes of 293 subjects who had their health examinations done in health examination center at a university hospital located in the Kyoung-gi province, from March 17, 2008 to April 16, 2008. According blood lipid levels given by a standard for treating hyperlipidemia, those who had blood cholesterol levels above 240ml/dl or triglyceride levels above 200ml/dl were put into risk group, those who had blood cholesterol levels below 200ml/dl and triglyceride levels below 150ml/dl were put into normal group, and those who were between the two groups in terms of the levels were put into borderline group. Calorie intake for the three groups were 1,818.3±22.5kcal, 1,803±36.3kcal, and 1,999.5±45.9kcal for the normal group, borderline group, and risk group, respectively. It showed that the risk group had significantly high intake amounts compared to the normal group. Furthermore, in the intake of carbohydrate, fat, protein, the risk group were significantly higher than the normal group. In the nutrition and cellulose intake for small amounts - excluding zinc - there were no significant differences among the three groups. The risk group had significantly higher averages of body mass index, weight, waist circumference, and % fat by body type compared to the normal group. Moreover, both systolic and diastolic blood pressure were significantly higher for the risk group than the normal group. There were no significant differences between the three groups depending on lifestyle behaviors, including smoking, exercise, and whether or not alcohol was consumed. Also, there were no significant differences among the three groups depending on dietary patterns. There were no significant differences between the three groups depending on lifestyle behaviors factors, including smoking, exercise, and whether or not alcohol was consumed. Also, there were no significant differences among the three groups depending on dietary patterns. After the analysis was done to find out the factors that contribute to blood lipid levels, for the subjects that answered in the affirmative for whether or not they still smoked, their triglyceride levels were significantly high, and those who said that they consumed alcohol every day had significantly high levels for both blood cholesterol and triglyceride. Meanwhile, after triglyceride and total cholesterol levels of the subjects were divided into borderline・risk triglyceride group and borderline・risk cholesterol group, and dietary intakes amounts were compared, the risk triglyceride group had significantly high calorie, carbohydrate, fat, and protein amounts. However, there were no significant differences for the risk cholesterol group. After analyzing the correlation between dietary intakes and blood lipid levels, calorie, carbohydrate, fat, protein intake amounts showed correlation to triglyceride levels and amounts. Furthermore, intake amounts on the day and HDL-cholesterol levels showed a negative correlation between them. But the others including body mass index, triglyceride, and total cholesterol all showed positive correlations. The results showed that amount of dietary intakes, body mass index, blood pressure, age, smoking, drinking, all affected blood lipid levels. It was found that, as for food intake, the more the amount of calorie, carbohydrate, fat, protein intake, the higher the blood lipid levels, and the more the amount of carbohydrate intake, the lower the HDL-cholesterol. Therefore, further studies need to be done on finding out each of the nutrients that Korean citizens consume with their current eating habits, and dietary intakes factors that affect blood lipid profile.
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